Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174178 | 0.76 | GRIN2B (0.30) | — | |
| SCHEMBL10509125 | 0.76 | — | — | |
| SCHEMBL2115152 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL11204101 | 0.71 | DPP4 (0.35) | — | |
| SCHEMBL933448 | 0.69 | — | — | |
| SCHEMBL16211124 | 0.69 | — | — | |
| SCHEMBL7290718 | 0.68 | FFAR3 (0.39) | FFAR3 | |
| SCHEMBL2367455 | 0.68 | GRIN2B (0.30) | — | |
| SCHEMBL239129 | 0.68 | GRIN2B (0.30) | — | |
| SCHEMBL77429 | 0.68 | GFER (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912146-B2 | Derivatives of APF and methods of use | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-12-16 | — | — | US | disclosed |
| WO-2014127052-A1 | PERFLUORO-TERT-BUTYL HYDROXYPROLINE | ZONDLO NEAL (US) | 2014-08-21 | — | — | WO | disclosed |
| US-20120094933-A1 | DERIVATIVES OF APF AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-19 | — | — | US | disclosed |
| EP-2328603-A2 | DERIVATIVES OF APF AND METHODS OF USE | University of Maryland, Baltimore (US) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010022089-A9 | DERIVATIVES OF APF AND METHODS OF USE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010022089-A2 | DERIVATIVES OF APF AND METHODS OF USE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094933-A1 | DERIVATIVES OF APF AND METHODS OF USE | APLNR, ETF1, VIP | FFAR3 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.