SCHEMBL20339315

SCHEMBL20339315

[N-]=[N+]=NCc1ccc(CC(N)C(=O)O)cn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.47
▸ SLC7A5 Q01650 3/20 0.44
▸ PTGS1 P23219 3/20 0.43
▸ PKM P14618 2/20 0.43
▸ ALPI P09923 1/20 0.43
▸ XIAP P98170 1/20 0.43
▸ TPH1 P17752 1/20 0.42
▸ HIF1A Q16665 5/20 0.41
▸ ALOX15 P16050 3/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ EGFR P00533 1/20 0.41
▸ LCK P06239 1/20 0.41
▸ FYN P06241 1/20 0.41
▸ ADORA3 P0DMS8 1/20 0.41
▸ HTR2A P28223 1/20 0.41
▸ PTGS2 P35354 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ CYP3A4 P08684 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15469207 1.00 HSD17B10 (0.47) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL29373039 0.90 SLC7A5 (0.41) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL15469201 0.90 SLC7A5 (0.41) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL15511517 0.90 SLC7A5 (0.41) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL17814914 0.82 SLC7A5 (0.57) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL15469220 0.82 SLC7A5 (0.57) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL24248048 0.79 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL18995731 0.79 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL15495954 0.79 HSD17B10 (0.55) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL19198746 0.77 HSD17B10 (0.54) HSD17B10SLC7A5PTGS1PKMALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076210-A1 CHLAMYDIA VACCINE COMPOSITIONS VAXCYTE, INC. (US) 2025-04-10 — — WO claimed
US-20240358823-A1 CONJUGATED VACCINE CARRIER PROTEINS VAXCYTE, INC. 2024-10-31 — — US claimed
US-20240335521-A1 STABILIZATION OF ADJUVANTED VACCINE COMPOSITIONS AND THEIR USE VAXCYTE, INC. 2024-10-10 — — US claimed
CN-118662649-A Polypeptide-antigen conjugates with unnatural amino acids VAXCYTE公司 2024-09-20 — — CN claimed
EP-4395818-A1 STABILIZATION OF ADJUVANTED VACCINE COMPOSITIONS AND THEIR USE VAXCYTE, INC. (US) 2024-07-10 — — EP claimed
CN-117479961-A Purification method of polysaccharide and polypeptide conjugate thereof VAXCYTE公司 2024-01-30 — — CN claimed
US-20240000926-A1 PURIFICATION PROCESSES FOR POLYSACCHARIDES AND POLYPEPTIDE CONJUGATES THEREOF VAXCYTE, INC. 2024-01-04 — — US claimed
EP-4294452-A1 PURIFICATION PROCESSES FOR POLYSACCHARIDES AND POLYPEPTIDE CONJUGATES THEREOF VAXCYTE, INC. (US) 2023-12-27 — — EP claimed
US-20230293658-A1 GROUP A STREP IMMUNOGENIC COMPOSITIONS WITH POLYSACCHARIDE-PROTEIN CONJUGATES VAXCYTE, INC. 2023-09-21 — — US claimed
WO-2023034932-A1 STABILIZATION OF ADJUVANTED VACCINE COMPOSITIONS AND THEIR USE VAXCYTE, INC. (US) 2023-03-09 — — WO claimed
US-20220125907-A1 OPTIMIZED CELL-FREE SYNTHESIS OF INVASION PLASMID ANTIGEN B AND RELATED COMPOSITIONS AND METHODS OF USE VAXCYTE, INC. 2022-04-28 — — US claimed
EP-3946443-A1 OPTIMIZED CELL-FREE SYNTHESIS OF INVASION PLASMID ANTIGEN B AND RELATED COMPOSITIONS AND METHODS OF USE VAXCYTE, INC. (US) 2022-02-09 — — EP claimed
CN-114025789-A Optimized cell-free synthesis of invasive plasmid antigen B and related compositions and methods of use VAXCYTE公司 2022-02-08 — — CN claimed
WO-2020205584-A1 OPTIMIZED CELL-FREE SYNTHESIS OF INVASION PLASMID ANTIGEN B AND RELATED COMPOSITIONS AND METHODS OF USE VAXCYTE, INC. (US) 2020-10-08 — — WO claimed
US-20200054739-A1 CONJUGATED VACCINES SUTROVAX, INC. 2020-02-20 — — US claimed
EP-3562503-A2 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS Sutrovax, Inc. (US) 2019-11-06 — — EP claimed
CN-110366428-A Polypeptide-antigen conjugates with unnatural amino acids SUTROVAX公司 2019-10-22 — — CN claimed
WO-2018126229-A9 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS SUTROVAX, INC. (US) 2019-07-25 — — WO claimed
US-20180333484-A1 Polypeptide-Antigen Conjugates with Non-Natural Amino Acids SUTROVAX, INC. (US) 2018-11-22 — — US claimed
WO-2018126229-A2 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS SUTROVAX, INC. (US) 2018-07-05 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240000926-A1 PURIFICATION PROCESSES FOR POLYSACCHARIDES AND POLYPEPTIDE CONJUGATES THEREOF DDOST, ALG1, PAG1 HSD17B10 3804/4885SLC7A5 2269/4885PTGS1 3725/4885
US-20200054739-A1 CONJUGATED VACCINES ASNS, CD14, CD74 HSD17B10 2068/4885SLC7A5 129/4885PTGS1 3300/4885
US-20180333484-A1 Polypeptide-Antigen Conjugates with Non-Natural Amino Acids CD74, DNPEP, NGLY1 HSD17B10 3231/4885SLC7A5 227/4885PTGS1 3633/4885
US-20240358823-A1 CONJUGATED VACCINE CARRIER PROTEINS CD74, LY96, ASNS HSD17B10 2269/4885SLC7A5 91/4885PTGS1 3185/4885
US-20230293658-A1 GROUP A STREP IMMUNOGENIC COMPOSITIONS WITH POLYSACCHARIDE-PROTEIN CONJUGATES SIGLEC9, SIGLEC7, CD14 HSD17B10 4067/4885SLC7A5 2763/4885PTGS1 2058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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