SCHEMBL15469220

SCHEMBL15469220

[N-]=[N+]=NCc1ccc(C[C@H](N)C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 3/20 0.57
▸ PTGS1 P23219 3/20 0.56
▸ ALPI P09923 1/20 0.56
▸ PKM P14618 1/20 0.56
▸ XIAP P98170 1/20 0.56
▸ TPH1 P17752 3/20 0.53
▸ HIF1A Q16665 5/20 0.50
▸ CYP3A4 P08684 3/20 0.50
▸ ALOX15 P16050 3/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ ABCB11 O95342 1/20 0.50
▸ CHRM2 P08172 1/20 0.50
▸ ADRA2A P08913 1/20 0.50
▸ CHRM1 P11229 1/20 0.50
▸ ACHE P22303 1/20 0.50
▸ OPRM1 P35372 1/20 0.50
▸ DRD3 P35462 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17814914 1.00 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL23069024 0.85 NOS3 (0.55) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL23069027 0.85 NOS3 (0.55) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL22669502 0.84 GRIK1 (0.46) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL15511517 0.82 SLC7A5 (0.41) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL29373039 0.82 SLC7A5 (0.41) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL15469201 0.82 SLC7A5 (0.41) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL15469207 0.82 HSD17B10 (0.47) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL20339315 0.82 HSD17B10 (0.47) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL15469227 0.81 HSD17B10 (0.42) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689127-A1 RF1 KO E. COLI STRAINS Sutro Biopharma, Inc. (US) 2026-02-11 — — EP claimed
US-12540197-B2 Anti-tissue factor antibodies and antibody conjugates, compositions comprising anti-tissue factor antibodies or antibody conjugates, and methods of making and using anti-tissue factor antibodies and antibody conjugates SUTRO BIOPHARMA, INC. (US) 2026-02-03 — — US claimed
US-12534465-B2 5H-pyrrolo[3,2-d]pyrimidine-2,4-diamino compounds and antibody conjugates thereof SUTRO BIOPHARMA, INC. (US) 2026-01-27 — — US claimed
US-20250346650-A1 ANTIBODIES WITH ENGINEERED CH2 DOMAINS, COMPOSITIONS THEREOF AND METHODS OF USING THE SAME SUTRO BIOPHARMA INC (US) 2025-11-13 — — US claimed
US-20250325633-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES Synthorx, Inc. (US) 2025-10-23 — — US claimed
US-20250325632-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES Synthorx, Inc. (US) 2025-10-23 — — US claimed
US-20250304723-A1 MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. 2025-10-02 — — US claimed
US-12427201-B2 Anti-folate receptor antibody conjugates, compositions comprising anti-folate receptor antibody conjugates, and methods of making and using anti-folate receptor antibody conjugates SUTRO BIOPHARMA, INC. (US) 2025-09-30 — — US claimed
US-12421239-B2 — — 2025-09-23 — — US claimed
US-12398197-B2 Antibodies with engineered CH2 domains, compositions thereof and methods of using the same SUTRO BIOPHARMA, INC. (US) 2025-08-26 — — US claimed
WO-2018126229-A2 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS SUTROVAX, INC. (US) 2018-07-05 — — WO claimed
EP-3271359-A1 ISOQUINOLIDINOBENZODIAZEPINES Cellerant Therapeutics, Inc. (US) 2018-01-24 — — EP claimed
US-9764039-B2 Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use SUTRO BIOPHARMA, INC. (US) 2017-09-19 — — US claimed
US-9738724-B2 Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use SUTRO BIOPHARMA, INC. (US) 2017-08-22 — — US claimed
US-9732161-B2 Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use SUTRO BIOPHARMA, INC. (US) 2017-08-15 — — US claimed
WO-2017132617-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. (US) 2017-08-03 — — WO claimed
WO-2017132615-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. (US) 2017-08-03 — — WO claimed
WO-2016149546-A1 ISOQUINOLIDINOBENZODIAZEPINES CELLERANT THERAPEUTICS, INC. (US) 2016-09-22 — — WO claimed
EP-3055321-A1 NON-NATURAL AMINO ACID tRNA SYNTHETASES FOR PARA-METHYLAZIDO-L-PHENYLALANINE Sutro Biopharma, Inc. (US) 2016-08-17 — — EP claimed
WO-2015054587-A1 NON-NATURAL AMINO ACID tRNA SYNTHETASES FOR PARA-METHYLAZIDO-L-PHENYLALANINE SUTRO BIOPHARMA, INC. (US) 2015-04-16 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325633-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES IL2, IL2RA, IL15 SLC7A5 2484/4885PTGS1 1447/4885ALPI 1243/4885
US-12427201-B2 Anti-folate receptor antibody conjugates, compositions comprising anti-folate receptor antibody conjugates, and methods of making and using anti-folate receptor antibody conjugates FOLR1, FOLR2, DHFR SLC7A5 743/4885PTGS1 4083/4885ALPI 2698/4885
US-20250304723-A1 MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE FCGR2A, FCGR3B, FCGR1A SLC7A5 888/4885PTGS1 3984/4885ALPI 3252/4885
US-12421239-B2 — FCGRT, DPYD, CD2BP2 SLC7A5 2149/4885PTGS1 4683/4885ALPI 2040/4885
US-20250325632-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES IL2, IL2RA, IL36G SLC7A5 1836/4885PTGS1 1611/4885ALPI 506/4885
US-12534465-B2 5H-pyrrolo[3,2-d]pyrimidine-2,4-diamino compounds and antibody conjugates thereof CD22, FCGR3B, FCGR2A SLC7A5 689/4885PTGS1 2753/4885ALPI 2532/4885
US-12540197-B2 Anti-tissue factor antibodies and antibody conjugates, compositions comprising anti-tissue factor antibodies or antibody conjugates, and methods of making and using anti-tissue factor antibodies and antibody conjugates VSIG8, F13B, HNRNPH3 SLC7A5 1194/4885PTGS1 4003/4885ALPI 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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