Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250442 | 0.87 | MAPT (0.42) | MAPTTHRBALDH1A1NPSR1GAA | |
| SCHEMBL5256543 | 0.81 | MAPT (0.38) | MAPTTHRBALDH1A1NPSR1GAA | |
| SCHEMBL9254314 | 0.80 | ALDH1A1 (0.40) | MAPTTHRBALDH1A1NPSR1GAA | |
| SCHEMBL1984241 | 0.78 | CYP1A2 (0.52) | MAPTALDH1A1NPSR1GAAMCHR1 | |
| SCHEMBL28490785 | 0.77 | PTGES (0.46) | — | |
| SCHEMBL1030141 | 0.77 | ALDH1A1 (0.45) | MAPTTHRBALDH1A1NPSR1GAA | |
| SCHEMBL11624271 | 0.77 | ALDH1A1 (0.41) | MAPTALDH1A1NPSR1GAALMNA | |
| SCHEMBL6132178 | 0.77 | ALDH1A1 (0.45) | MAPTTHRBALDH1A1NPSR1GAA | |
| SCHEMBL27859464 | 0.77 | L3MBTL1 (0.37) | MAPTTHRBALDH1A1NPSR1GAA | |
| SCHEMBL4113689 | 0.76 | SMN1; SMN2 (0.54) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125524-A1 | DENDRITIC LIGANDS FOR CONTROLLING SELF ASSEMBLY AND SURFACE POLARITY OF NANOPARTICLES, AND HYBRID NANOPARTICLES PRODUCED THEREFROM | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-07-05 | — | — | WO | disclosed |