Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.96 |
| ▸ | TP53 | P04637 | 5/20 | 0.78 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | THRB | P10828 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | FLT3 | P36888 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706271 | 0.89 | MAPT (0.77) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL16784364 | 0.87 | MAPT (0.80) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL8206445 | 0.86 | TP53 (0.80) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL14748250 | 0.86 | MAPT (0.79) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL12443267 | 0.86 | MAPT (0.72) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL918663 | 0.82 | MEN1 (1.00) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL20339082 | 0.82 | MAPT (0.67) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL8289414 | 0.81 | FLT3 (0.96) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL20704645 | 0.81 | MAPT (0.70) | MAPTTP53NPC1MEN1KMT2A | |
| SCHEMBL21247366 | 0.80 | RAB9A (1.00) | MAPTTP53NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562818-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-05-18 | — | — | EP | claimed |
| CN-110114349-B | Thiophene derivatives as antiviral agents | 埃尼奥制药公司 | 2022-03-15 | — | — | CN | claimed |
| US-20190352275-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2019-11-21 | — | — | US | claimed |
| EP-3562818-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | Enyo Pharma (FR) | 2019-11-06 | — | — | EP | claimed |
| WO-2018122317-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2018-07-05 | — | — | WO | claimed |
| US-11807618-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2023-11-07 | — | — | US | disclosed |
| US-20220213053-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-07-07 | — | — | US | disclosed |
| EP-3562818-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-05-18 | — | — | EP | disclosed |
| US-11279683-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2022-03-22 | — | — | US | disclosed |
| CN-110114349-B | Thiophene derivatives as antiviral agents | 埃尼奥制药公司 | 2022-03-15 | — | — | CN | disclosed |
| US-20190352275-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2019-11-21 | — | — | US | disclosed |
| EP-3562818-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | Enyo Pharma (FR) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018122317-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2018-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213053-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | MAVS, EIF2AK2, IRF3 | MAPT 3934/4885TP53 1353/4885NPC1 970/4885 |
| US-11279683-B2 | Thiophene derivatives as antiviral agents | MAVS, EIF2AK2, IRF3 | MAPT 4150/4885TP53 2656/4885NPC1 444/4885 |
| US-20190352275-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | MAVS, EIF2AK2, IRF3 | MAPT 4150/4885TP53 2656/4885NPC1 444/4885 |
| US-11807618-B2 | Thiophene derivatives as antiviral agents | MAVS, EIF2AK2, IRF3 | MAPT 3934/4885TP53 1353/4885NPC1 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.