Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340487 | 0.89 | RAB9A (0.36) | RAB9ACYP3A4HPGDCYP2C19JAK2 | |
| SCHEMBL5067337 | 0.89 | RAB9A (0.49) | RAB9ACYP3A4HPGDCYP2C19JAK2 | |
| SCHEMBL18199497 | 0.89 | RAB9A (0.49) | RAB9ACYP3A4HPGDCYP2C19JAK2 | |
| SCHEMBL15014614 | 0.81 | EPHX1 (0.48) | RAB9ACYP3A4HPGDCYP2C19EPHX1 | |
| SCHEMBL15014593 | 0.81 | EPHX1 (0.48) | RAB9ACYP3A4HPGDCYP2C19EPHX1 | |
| SCHEMBL23197739 | 0.81 | HTT (0.43) | RAB9ACYP3A4HPGDCYP2C19EPHX1 | |
| SCHEMBL11890375 | 0.81 | RAB9A (0.58) | RAB9ACYP3A4HPGDCYP2C19EPHX1 | |
| SCHEMBL15119348 | 0.81 | HTT (0.47) | RAB9ACYP3A4HPGDCYP2C19EPHX1 | |
| SCHEMBL11890370 | 0.81 | RAB9A (0.54) | RAB9ACYP3A4HPGDCYP2C19EPHX1 | |
| SCHEMBL12384535 | 0.80 | RAB9A (0.43) | RAB9ACYP3A4HPGDCYP2C19JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207363-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2024-06-27 | — | — | US | disclosed |
| US-10039809-B2 | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-08-07 | — | — | US | disclosed |
| US-10010589-B2 | — | — | 2018-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010589-B2 | — | TYMP, MTAP, TUBB6 | RAB9A 2342/4885CYP3A4 4850/4885HPGD 1325/4885 |
| US-20240207363-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | SGMS1, SGMS2, PHOSPHO1 | RAB9A 897/4885CYP3A4 4869/4885HPGD 4004/4885 |
| US-10039809-B2 | Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof | SGMS1, SGMS2, PHOSPHO1 | RAB9A 897/4885CYP3A4 4869/4885HPGD 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.