SCHEMBL20340673

SCHEMBL20340673

CCCOC(=O)Nc1ccc2nn[nH]c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 8/20 0.50
SMN1; SMN2 Q16637 8/20 0.49
ALDH1A1 P00352 3/20 0.49
MAPK1 P28482 2/20 0.49
TUBB4A P04350 1/20 0.46
TUBB P07437 1/20 0.46
TUBA3C P0DPH7 1/20 0.46
TUBA1B P68363 1/20 0.46
TUBA4A P68366 1/20 0.46
TUBB4B P68371 1/20 0.46
TUBB3 Q13509 1/20 0.46
TUBB2A Q13885 1/20 0.46
TUBB8 Q3ZCM7 1/20 0.46
TUBA3E Q6PEY2 1/20 0.46
TUBA1A Q71U36 1/20 0.46
TUBA1C Q9BQE3 1/20 0.46
TUBB6 Q9BUF5 1/20 0.46
TUBB2B Q9BVA1 1/20 0.46
TUBB1 Q9H4B7 1/20 0.46
RAB9A P51151 8/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8021163 0.79 ELANE (0.51) HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A
SCHEMBL11307021 0.78 KDM4E (0.51) HPGDSMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL20306812 0.77 ALDH1A1 (0.49) HPGDALDH1A1KDRLMNAMAPT
SCHEMBL3957761 0.76 LMNA (0.52) HPGDSMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL13411810 0.75 ALDH1A1 (0.51) SMN1; SMN2ALDH1A1TP53CYP1A2LMNA
SCHEMBL13744148 0.75 ALDH1A1 (0.50) HPGDSMN1; SMN2ALDH1A1RAB9ANPC1
SCHEMBL14141176 0.75 KDM4E (0.38) HPGDSMN1; SMN2ALDH1A1RAB9ATP53
SCHEMBL7562459 0.75 SMN1; SMN2 (0.77) HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A
SCHEMBL20306813 0.75 LMNA (0.41) HPGDALDH1A1KDRLMNAMAPT
SCHEMBL13715799 0.75 KIF11 (0.43) ALDH1A1NPC1EGFRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10014474-B2 Composition for forming gate insulating film, organic thin film transistor, electronic paper, and display device FUJIFILM CORPORATION (JP) 2018-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10014474-B2 Composition for forming gate insulating film, organic thin film transistor, electronic paper, and display device TEC, EPCAM, MIF HPGD 4696/4885SMN1; SMN2 4744/4885ALDH1A1 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.