Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23810241 | 1.00 | CTSL (0.40) | CTSLCTSBCTSSBDKRB1NAMPT | |
| SCHEMBL18616494 | 0.87 | CTSL (0.43) | CTSLCTSBCTSSBDKRB1NAMPT | |
| SCHEMBL18616007 | 0.83 | CTSL (0.45) | CTSLCTSBCTSSBDKRB1NAMPT | |
| SCHEMBL18616640 | 0.82 | ACACB (0.31) | CTSLCTSBCTSS | |
| SCHEMBL20341777 | 0.74 | TACR2 (0.32) | — | |
| SCHEMBL20341822 | 0.74 | CTSS (0.32) | CTSS | |
| SCHEMBL23810242 | 0.74 | NAMPT (0.40) | NAMPT | |
| SCHEMBL20341848 | 0.72 | CTSS (0.31) | CTSS | |
| SCHEMBL23810314 | 0.72 | TP53 (0.33) | — | |
| SCHEMBL20341768 | 0.71 | ERN1 (0.39) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |