Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616007 | 0.87 | CTSL (0.45) | CTSLCTSBCTSSNAMPTBDKRB1 | |
| SCHEMBL20341821 | 0.87 | CTSL (0.40) | CTSLCTSBCTSSNAMPTBDKRB1 | |
| SCHEMBL23810241 | 0.87 | CTSL (0.40) | CTSLCTSBCTSSNAMPTBDKRB1 | |
| SCHEMBL20341790 | 0.82 | NAMPT (0.42) | NAMPTPOLBERAP1 | |
| SCHEMBL20341745 | 0.82 | SMN1; SMN2 (0.42) | HDAC6 | |
| SCHEMBL18615936 | 0.77 | MAOA (0.33) | — | |
| SCHEMBL20341862 | 0.77 | BMPR1B (0.36) | HDAC6ROCK2 | |
| SCHEMBL18615931 | 0.75 | CTSS (0.36) | CTSLCTSBCTSSERAP1 | |
| SCHEMBL18615951 | 0.74 | BMPR1B (0.35) | HDAC6ROCK2 | |
| SCHEMBL20341831 | 0.73 | MAPT (0.32) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |