Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.38 |
| ▸ | CTSS | P25774 | 8/20 | 0.38 |
| ▸ | CTSB | P07858 | 7/20 | 0.38 |
| ▸ | TACR2 | P21452 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20341776 | 0.92 | ACACB (0.32) | CTSLCTSSCTSBACACB | |
| SCHEMBL18615855 | 0.84 | CTSL (0.36) | CTSLCTSSCTSBCTSKACACB | |
| SCHEMBL23810263 | 0.81 | CTSS (0.35) | CTSLCTSSCTSBTACR2CTSK | |
| SCHEMBL23810243 | 0.80 | CTSL (0.46) | CTSLCTSSCTSBTACR2CTSK | |
| SCHEMBL20341858 | 0.79 | CTSL (0.35) | CTSLCTSSCTSBTACR2CTSK | |
| SCHEMBL18616514 | 0.79 | CTSL (0.45) | CTSLCTSSCTSBTACR2CTSK | |
| SCHEMBL23810312 | 0.78 | CTSL (0.49) | CTSLCTSSCTSBTACR2CTSK | |
| SCHEMBL18616800 | 0.76 | CTSL (0.42) | CTSLCTSSCTSBTACR2CTSK | |
| SCHEMBL23810245 | 0.76 | ACACB (0.33) | CTSLCTSSCTSBTACR2ACACB | |
| SCHEMBL18616640 | 0.76 | ACACB (0.31) | CTSLCTSSCTSBACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |