Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615855 | 0.92 | CTSL (0.36) | ACACBCTSLCTSBCTSSCACNA1G | |
| SCHEMBL20341849 | 0.92 | CTSL (0.38) | ACACBCTSLCTSBCTSS | |
| SCHEMBL23810245 | 0.84 | ACACB (0.33) | ACACBCTSLCTSBCTSS | |
| SCHEMBL18616640 | 0.84 | ACACB (0.31) | ACACBCTSLCTSBCTSS | |
| SCHEMBL23810282 | 0.83 | CTSL (0.42) | ACACBCTSLCTSBCTSSCACNA1H | |
| SCHEMBL18616019 | 0.83 | ACACB (0.38) | ACACBCACNA1GCACNA1HCACNA1I | |
| SCHEMBL18616645 | 0.82 | CTSS (0.39) | CTSLCTSBCTSSCACNA1H | |
| SCHEMBL20335400 | 0.82 | CTSL (0.39) | CTSLCTSBCTSSCACNA1H | |
| SCHEMBL23810291 | 0.80 | — | — | |
| SCHEMBL20341846 | 0.80 | CTSL (0.37) | CTSLCTSBCTSSCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |