Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 6/20 | 0.69 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.69 |
| ▸ | TRPM2 | O94759 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320685 | 0.87 | ALDH1A1 (0.76) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL2851492 | 0.85 | MMP1 (0.75) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL30538697 | 0.85 | MMP1 (0.75) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL2851499 | 0.85 | MMP1 (0.75) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL30335821 | 0.85 | MMP1 (0.75) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL28810850 | 0.84 | TRPA1 (0.66) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL28810848 | 0.84 | TRPA1 (0.66) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL13854017 | 0.83 | TRPA1 (0.69) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL12723664 | 0.82 | TRPA1 (0.65) | TRPA1TRPM8TRPM2MEN1KMT2A | |
| SCHEMBL6517926 | 0.82 | TRPA1 (1.00) | TRPA1TRPM8TRPM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799427-B1 | Therapeutic compounds | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2018-07-04 | — | — | EP | disclosed |