Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 4/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2604655 | 0.93 | TYMS (0.41) | TYMSPOLBTSHRMAPK1 | |
| SCHEMBL9607776 | 0.89 | ERN1 (0.40) | ESR2TYMSPOLBTSHRMAPK1 | |
| SCHEMBL2604627 | 0.89 | CYP1A2 (0.44) | TYMS | |
| SCHEMBL2604656 | 0.88 | ERN1 (0.39) | ESR2PTGER2TYMSPOLBTSHR | |
| SCHEMBL2604623 | 0.84 | ERN1 (0.36) | ESR2TYMSPOLBTSHRMAPK1 | |
| SCHEMBL9613625 | 0.84 | THRB (0.43) | TYMSPOLBTSHRMAPK1 | |
| SCHEMBL7417795 | 0.83 | TSHR (0.49) | TYMSPOLBTSHRMAPK1 | |
| SCHEMBL16488179 | 0.82 | KDM4E (0.47) | ESR2 | |
| SCHEMBL3438601 | 0.82 | ERN1 (0.39) | ESR2TYMSPOLBTSHRMAPK1 | |
| SCHEMBL18808272 | 0.82 | ERN1 (0.51) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3121247-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-10-02 | — | — | EP | disclosed |
| EP-3067405-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-03-27 | — | — | EP | disclosed |
| EP-2703472-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2018-07-04 | — | — | EP | disclosed |