Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 9/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 6/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15077584 | 0.96 | HSD11B1 (0.46) | HSD11B1JAK3ALDH1A1CYP3A4JAK1 | |
| SCHEMBL16199664 | 0.81 | JAK2 (0.39) | HSD11B1JAK1KMT2AMEN1MAPT | |
| SCHEMBL20343397 | 0.81 | JAK2 (0.39) | HSD11B1JAK1KMT2AMEN1MAPT | |
| SCHEMBL20343457 | 0.81 | JAK1 (0.41) | JAK3ALDH1A1CYP3A4JAK1KMT2A | |
| SCHEMBL22754623 | 0.80 | JAK1 (0.40) | JAK3ALDH1A1CYP3A4JAK1JAK2 | |
| SCHEMBL20082804 | 0.78 | JAK1 (0.43) | JAK3ALDH1A1JAK1KMT2AMEN1 | |
| SCHEMBL22007556 | 0.78 | JAK1 (0.43) | JAK3ALDH1A1JAK1KMT2AMEN1 | |
| SCHEMBL20343491 | 0.78 | JAK1 (0.43) | JAK3ALDH1A1JAK1KMT2AMEN1 | |
| SCHEMBL1899294 | 0.78 | ALDH1A1 (0.38) | HSD11B1JAK3ALDH1A1CYP3A4JAK1 | |
| SCHEMBL20082891 | 0.77 | HSD11B1 (0.33) | HSD11B1ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796460-B1 | PYRROLE SIX-MEMBERED HETEROARYL RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICINAL USES THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2018-07-04 | — | — | EP | disclosed |