Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035250 | 1.00 | TBXAS1 (0.48) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2D6 | |
| Dl-Phenylalanine SCHEMBL28957563 | 0.95 | PKM (0.55) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL29417369 | 0.85 | FDPS (0.54) | CYP1A2CYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL30801039 | 0.85 | SLC7A5 (0.65) | TBXAS1CYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL29432890 | 0.85 | SLC7A5 (0.65) | TBXAS1CYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL44077 | 0.85 | FDPS (0.54) | CYP1A2CYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL503440 | 0.85 | FDPS (0.54) | CYP1A2CYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL124364 | 0.85 | SLC7A5 (0.65) | TBXAS1CYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL124365 | 0.85 | SLC7A5 (0.65) | TBXAS1CYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL5056888 | 0.85 | SLC7A5 (0.65) | TBXAS1CYP1A2CYP3A4CYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110236429-A1 | Small Cationic Antimicrobial Peptides | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-09-29 | — | — | US | disclosed |
| US-20110150917-A1 | Small Cationic Antimicrobial Peptides | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-06-23 | — | — | US | disclosed |
| WO-2008151434-A1 | SMALL CATIONIC ANTIMICROBIAL PEPTIDES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-12-18 | — | — | WO | disclosed |