SCHEMBL20344349

SCHEMBL20344349

COC(=O)c1cc(-c2ccc3c(c2)C(=O)OC3=O)ccc1C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 0.43
CHEK1 O14757 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
ROCK2 O75116 1/20 0.40
CSF1R P07333 1/20 0.40
KDR P35968 1/20 0.40
FLT3 P36888 1/20 0.40
GSK3A P49840 1/20 0.40
GSK3B P49841 1/20 0.40
CDK5 Q00535 1/20 0.40
ROCK1 Q13464 1/20 0.40
SLK Q9H2G2 1/20 0.40
IRAK4 Q9NWZ3 1/20 0.40
KDM4E B2RXH2 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19494829 0.90 ERN1 (0.46) ERN1CHEK1CA12CA1CA7
SCHEMBL1709746 0.85 CHEK1 (0.47) CHEK1CA12CA1CA7ROCK2
SCHEMBL22176451 0.85 CA2 (0.43) CA12CA1CA7KDM4ECYP1A2
SCHEMBL14530973 0.85 CA12 (0.46) ERN1CA12CA1CA7KDM4E
SCHEMBL24063953 0.84 ALDH1A1 (0.47) ERN1CA12CA1CA7ROCK2
SCHEMBL20344311 0.84 SLC6A3 (0.41) ERN1ROCK2CSF1RKDRFLT3
SCHEMBL18537723 0.84 CA2 (0.42) ERN1CA12CA1CA7KDM4E
SCHEMBL12053214 0.83 CA12 (0.43) ERN1CA12CA1CA7KDM4E
SCHEMBL18807680 0.83 CA2 (0.42) CA12CA1CA7KDM4ECYP1A2
SCHEMBL21423118 0.82 ALDH1A1 (0.41) ERN1CA12CA1CA7KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023074570-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-05-04 WO disclosed
EP-2358803-B1 CONTAINER AND COMPOSITION WITH DIESTER GAS BARRIER ENHANCING COMPOUNDS COCA COLA CO (US) 2021-06-30 EP disclosed
WO-2021070714-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2021-04-15 WO disclosed
EP-2636056-B1 POLYIMIDES AS DIELECTRIC BASF SE (DE) 2018-07-04 EP disclosed