Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034451 | 1.00 | IDO1 (0.47) | IDO1PAMMAOBHTR2APTGER4 | |
| SCHEMBL163963 | 0.76 | MAOB (0.67) | IDO1PAMMAOBHTR2APTGER4 | |
| SCHEMBL4256257 | 0.76 | MAOB (0.67) | IDO1PAMMAOBHTR2APTGER4 | |
| SCHEMBL1892917 | 0.76 | MAOB (0.67) | IDO1PAMMAOBHTR2APTGER4 | |
| SCHEMBL4863423 | 0.75 | IDO1 (0.58) | IDO1PAMMAOBHTR2ANPC1 | |
| SCHEMBL9777486 | 0.75 | IDO1 (0.58) | IDO1PAMMAOBHTR2ANPC1 | |
| Fluoride SCHEMBL28109078 | 0.74 | MAOB (0.64) | IDO1PAMMAOBHTR2APTGER4 | |
| SCHEMBL27480477 | 0.74 | IDO1 (0.40) | IDO1PAMMAOBHTR2APTGER4 | |
| SCHEMBL1870 | 0.73 | IDO1 (0.52) | IDO1PAMMAOBHTR2APTGER4 | |
| SCHEMBL1871 | 0.73 | IDO1 (0.52) | IDO1PAMMAOBHTR2APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696620-B2 | Antimicrobial compounds | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2020-06-30 | — | — | US | disclosed |
| US-20180290963-A1 | ANTIMICROBIAL COMPOUNDS | BOULOS, RAMIZ (AU) | 2018-10-11 | — | — | US | disclosed |
| US-9738591-B2 | Antimicrobial compounds | Boulos, Ramiz (AU) | 2017-08-22 | — | — | US | disclosed |
| US-20170029359-A1 | ANTIMICROBIAL COMPOUNDS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2017-02-02 | — | — | US | disclosed |
| US-20150189873-A1 | ANTIMICROBIAL COMPOUNDS | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2015-07-09 | — | — | US | disclosed |
| US-9023892-B2 | Antimicrobial compounds | Boulos, Ramiz (AU) | 2015-05-05 | — | — | US | disclosed |
| US-20120329871-A1 | ANTIMICROBIAL COMPOUNDS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2012-12-27 | — | — | US | disclosed |
| WO-2011075766-A1 | ANTIMICROBIAL COMPOUNDS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180290963-A1 | ANTIMICROBIAL COMPOUNDS | MRPL21, SPOUT1, MPO | IDO1 3284/4885PAM 2268/4885MAOB 1409/4885 |
| US-10696620-B2 | Antimicrobial compounds | MRPL21, SPOUT1, MPO | IDO1 3284/4885PAM 2268/4885MAOB 1409/4885 |
| US-20120329871-A1 | ANTIMICROBIAL COMPOUNDS | DPM1, NACA, CLPP | IDO1 3566/4885PAM 276/4885MAOB 2022/4885 |
| US-20170029359-A1 | ANTIMICROBIAL COMPOUNDS | MRPL21, SPOUT1, MPO | IDO1 3284/4885PAM 2268/4885MAOB 1409/4885 |
| US-20150189873-A1 | ANTIMICROBIAL COMPOUNDS | DPM1, NACA, CLPP | IDO1 3566/4885PAM 276/4885MAOB 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.