Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL6 | P05231 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22620679 | 0.87 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29558672 | 0.87 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL5350677 | 0.83 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL536090 | 0.82 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL67207 | 0.82 | NFKB1 (0.57) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29417728 | 0.82 | NFKB1 (0.57) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL26703568 | 0.82 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL17103316 | 0.78 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL28796222 | 0.78 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| Formaldehyde SCHEMBL28869544 | 0.78 | TDP1 (0.50) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113618-B1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2018-07-04 | — | — | EP | disclosed |