SCHEMBL20344798

SCHEMBL20344798

C=CCN1C(=O)CCc2cc(NS(=O)(=O)Cc3ccc(C)cc3)ccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.41
CREBBP Q92793 1/20 0.41
TRIM24 O15164 4/20 0.39
BRPF1 P55201 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
MAPT P10636 4/20 0.37
TP53 P04637 3/20 0.37
ALDH1A1 P00352 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
THRB P10828 1/20 0.36
MAPK1 P28482 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20344743 0.87 BRD4 (0.38) BRD4CREBBPTRIM24BRPF1HDAC1
SCHEMBL17771426 0.87 BRD4 (0.52) BRD4CREBBPTRIM24BRPF1HDAC1
SCHEMBL15298954 0.85 BRD4 (0.44) BRD4CREBBPTRIM24BRPF1HDAC1
SCHEMBL18099361 0.84 KMT2A (0.42) BRD4BRPF1HDAC1HDAC8HDAC6
SCHEMBL17771427 0.84 CES2 (0.50) BRD4CREBBPTRIM24BRPF1HDAC1
SCHEMBL18099368 0.84 BRD4 (0.37) BRD4BRPF1HDAC1HDAC8HDAC6
SCHEMBL17771425 0.84 BRD4 (0.57) BRD4CREBBPTRIM24BRPF1HDAC1
SCHEMBL17771429 0.83 POLB (0.51) BRD4HDAC1HDAC8HDAC6MAPT
SCHEMBL17771424 0.83 DRD2 (0.44) BRD4CREBBPTRIM24BRPF1HDAC1
SCHEMBL18571093 0.83 KMT2A (0.41) BRD4BRPF1HDAC1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3342766-B1 SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2020-12-09 EP disclosed
US-10842151-B2 Small molecule compound for enhancing plant stress resistance CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2020-11-24 US disclosed
EP-3342766-A1 SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) 2018-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10842151-B2 Small molecule compound for enhancing plant stress resistance CYP4F11, RICTOR, MYB BRD4 1887/4885CREBBP 100/4885TRIM24 4017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.