Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22216655 | 0.87 | NT5E (0.48) | L3MBTL1ALDH1A1TRPV4MEN1KMT2A | |
| SCHEMBL24835820 | 0.78 | NT5E (0.49) | L3MBTL1ALDH1A1TRPV4MEN1KMT2A | |
| SCHEMBL11608795 | 0.77 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1TRPV4MEN1KMT2A | |
| SCHEMBL20066468 | 0.76 | ALDH1A1 (0.56) | ALDH1A1TRPV4MEN1KMT2AGAA | |
| SCHEMBL20350708 | 0.76 | NT5E (0.47) | L3MBTL1ALDH1A1TRPV4KDM4EHPGD | |
| Oxalic Acid SCHEMBL11606518 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TRPV4MEN1KMT2AGAA | |
| SCHEMBL20347152 | 0.72 | CTBP2 (0.43) | ALDH1A1KMT2ACYP3A4KDM4E | |
| SCHEMBL20347267 | 0.71 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ANPSR1ATM | |
| SCHEMBL18808227 | 0.71 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1TSHRSIGMAR1KDM4E | |
| SCHEMBL10084675 | 0.70 | L3MBTL1 (0.97) | L3MBTL1ALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186827-A1 | Ectonucleotidase Inhibitors and Methods of Use Thereof | ANTENGENE THERAPEUTICS LIMITED (CN) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186827-A1 | Ectonucleotidase Inhibitors and Methods of Use Thereof | NT5E, ENTPD5, NT5C2 | L3MBTL1 4683/4885ALDH1A1 527/4885TRPV4 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.