Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910903 | 0.80 | LOXL2 (0.47) | LOXL2SYKKDM4EALDH1A1 | |
| SCHEMBL17818945 | 0.80 | LOXL2 (0.47) | LOXL2P2RX7 | |
| SCHEMBL18361828 | 0.80 | LOXL2 (0.44) | LOXL2HTR2CSYKCYP1A2P2RX7 | |
| SCHEMBL24109889 | 0.76 | HTR2A (0.37) | HTR2AHTR2CCYP2A6CYP1A2FABP4 | |
| SCHEMBL29576458 | 0.73 | LOXL2 (0.39) | LOXL2SYKP2RX7KDM4E | |
| SCHEMBL28985523 | 0.73 | HTR2A (0.35) | HTR2AHTR2CFABP4KDM4EALDH1A1 | |
| SCHEMBL28584463 | 0.72 | DRD2 (0.50) | LOXL2HTR2ADRD2SLC6A4SCD | |
| SCHEMBL9130183 | 0.69 | ABL1 (0.42) | HTR2AHTR2CCYP2A6CYP1A2FABP4 | |
| SCHEMBL9130179 | 0.69 | ABL1 (0.42) | HTR2AHTR2CCYP2A6CYP1A2FABP4 | |
| SCHEMBL24110509 | 0.69 | HTR2A (0.36) | HTR2AHTR2CCYP2A6CYP1A2FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | LOXL2 1/4885HTR2A 2333/4885HTR2C 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.