SCHEMBL203500

SCHEMBL203500

CC(=O)Oc1ccc(C=O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.61
MAPT P10636 5/20 0.61
KDM4E B2RXH2 4/20 0.61
LMNA P02545 3/20 0.61
MEN1 O00255 2/20 0.61
TTR P02766 1/20 0.61
TP53 P04637 1/20 0.61
CYP3A4 P08684 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ALDH1A1 P00352 5/20 0.56
CYP2A6 P11509 1/20 0.56
POLB P06746 1/20 0.53
PKM P14618 1/20 0.53
ELANE P08246 1/20 0.52
TUBB4A P04350 1/20 0.51
TUBB P07437 1/20 0.51
TUBA3C P0DPH7 1/20 0.51
TUBA1B P68363 1/20 0.51
TUBA4A P68366 1/20 0.51
TUBB4B P68371 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL3155393 0.96 KMT2A (0.59) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL6790494 0.94 HSD17B10 (0.59) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL7013877 0.92 ELANE (0.65) KMT2AMAPTKDM4ELMNAMEN1
4-Hydroxybenzaldehyde SCHEMBL9418057 0.92 ALDH5A1 (0.59) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL8009088 0.89 ALDH1A1 (0.58) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL11354408 0.84 MAPT (0.81) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL6243024 0.84 KMT2A (0.60) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL10941162 0.84 MAPT (0.81) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL2451780 0.84 MAPT (0.81) KMT2AMAPTKDM4ELMNAMEN1
SCHEMBL269329 0.83 LMNA (0.80) KMT2AMAPTKDM4ELMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230391828-A1 REGULATORS OF CELL DIVISION TECHNISCHE UNIVERSITAT DRESDEN (DE) 2023-12-07 US claimed
EP-4225780-A2 REGULATORS OF CELL DIVISION Technische Universität Dresden (DE) 2023-08-16 EP claimed
CN-113336645-B Method for synthesizing p-acetoxystyrene by one-pot method 上海博栋化学科技有限公司 2023-06-27 CN claimed
US-20230118467-A1 COSMETIC OR PHARMACEUTICAL USE OF AVENANTHRAMIDE L SYMRISE AG (DE) 2023-04-20 US claimed
EP-4114353-A1 COSMETIC OR PHARMACEUTICAL USE OF AVENANTHRAMIDE L Symrise AG (DE) 2023-01-11 EP claimed
CN-113527236-B Method for preparing amiodarone hydrochloride 苏州弘森药业股份有限公司 2022-12-23 CN claimed
WO-2022074072-A2 REGULATORS OF CELL DIVISION Technische Universität Dresden (DE) 2022-04-14 WO claimed
CN-109438326-B Fluorescent probe for detecting carboxylesterase, preparation method thereof and special detection kit 潍坊医学院 2022-02-15 CN claimed
CN-113336645-A Method for synthesizing p-acetoxystyrene by one-pot method 上海博栋化学科技有限公司 2021-09-03 CN claimed
CN-107722146-B Method for producing solid polyaluminoxane composition 三井化学株式会社 2021-02-26 CN claimed
WO-2003022860-A1 SYNTHETIC HEPARIN PENTASACCHARIDES ALCHEMIA PTY LTD (AU) 2003-03-20 WO claimed
WO-2002083123-A1 AURONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-10-24 WO claimed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US claimed
EP-0674232-B1 Recording sheets XEROX CORP (US) 2000-05-31 EP claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
US-5663022-A Recording sheets XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
US-5002699-A Electrically conducting polymers and complexes HONEYWELL INC. (US) 1991-03-26 US claimed
US-4483861-A Antihypertensive sulfur-containing compounds SANTEN PHARMACEUTICAL CO., LTD. (JP) 1984-11-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230118467-A1 COSMETIC OR PHARMACEUTICAL USE OF AVENANTHRAMIDE L TACR1, NPSR1, TACR2 KMT2A 2632/4885MAPT 991/4885KDM4E 4589/4885
US-20230391828-A1 REGULATORS OF CELL DIVISION PCNA, BOD1L1, MKI67 KMT2A 3967/4885MAPT 4162/4885KDM4E 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.