Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20351069 | 0.83 | KMT2A (0.40) | MAPTKDM4ETSHRGFERACMSD | |
| SCHEMBL20339819 | 0.80 | BRD4 (0.40) | BRD4MAPTKDM4ETSHRGFER | |
| SCHEMBL20339967 | 0.79 | ACMSD (0.58) | ADORA2AADORA1ACMSDKMT2AMEN1 | |
| SCHEMBL20350868 | 0.74 | ACMSD (0.42) | BRD4MAPTKDM4ETSHRGFER | |
| SCHEMBL26847198 | 0.73 | KMT2A (0.45) | KDM4ETSHRGFERACMSDKMT2A | |
| SCHEMBL20350857 | 0.72 | ACMSD (0.56) | ADORA2AADORA1ACMSDKMT2AMEN1 | |
| SCHEMBL26847367 | 0.72 | KMT2A (0.40) | KDM4ETSHRGFERACMSDKMT2A | |
| SCHEMBL20340155 | 0.71 | ACMSD (0.59) | TSHRADORA2AADORA1ACMSDKMT2A | |
| SCHEMBL18455367 | 0.70 | NISCH (0.49) | TSHRKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL24087882 | 0.70 | ACMSD (0.55) | KDM4ETSHRGFERACMSDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |