Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 5/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20350877 | 0.83 | BRD4 (0.40) | KMT2APOLBMEN1ACMSDTNF | |
| SCHEMBL26847307 | 0.81 | KMT2A (0.39) | KMT2APOLBMEN1ACMSDTNF | |
| SCHEMBL20340099 | 0.80 | KMT2A (0.40) | KMT2APOLBMEN1ACMSDTNF | |
| SCHEMBL24088036 | 0.80 | ACMSD (0.53) | KMT2APOLBMEN1ACMSDTNF | |
| SCHEMBL26847205 | 0.79 | KMT2A (0.43) | KMT2APOLBMEN1ACMSDTNF | |
| SCHEMBL20340101 | 0.77 | ACMSD (0.57) | KMT2APOLBMEN1ACMSDALDH1A1 | |
| SCHEMBL23849883 | 0.77 | ACMSD (0.48) | KMT2APOLBMEN1ACMSDTNF | |
| SCHEMBL24088135 | 0.75 | ACMSD (0.39) | KMT2APOLBMEN1ACMSDTNF | |
| SCHEMBL26847316 | 0.75 | ACMSD (0.39) | KMT2APOLBMEN1ACMSDTNF | |
| SCHEMBL24087880 | 0.73 | ALDH1A1 (0.42) | KMT2AACMSDALDH1A1HPGDHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |