Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340026 | 0.87 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL20340117 | 0.84 | KDM4E (0.57) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL20350879 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL20350844 | 0.79 | KDM4E (0.39) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL20340086 | 0.78 | HSD11B1 (0.33) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL20350871 | 0.77 | KDM4E (0.38) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL20340085 | 0.74 | KDM4E (0.44) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL20339960 | 0.71 | KDM4E (0.38) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL23183403 | 0.71 | KDM4E (0.32) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL20340035 | 0.70 | KDM4E (0.61) | ALDH1A1HPGDKDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125983-A1 | OXOPYRIDINE DERIVATIVES USEFUL AS AMINOCARBOXYMUCONATE SEMIALDEHYDE DECARBOXYLASE (ACMSD) INHIBITORS | MITOBRIDGE, INC. (US) | 2018-07-05 | — | — | WO | disclosed |