Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 12/20 | 0.71 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21571639 | 0.83 | PAICS (1.00) | PAICS | |
| SCHEMBL21571620 | 0.66 | PAICS (0.73) | PAICS | |
| SCHEMBL20352046 | 0.65 | PAICS (0.49) | PAICSMET | |
| SCHEMBL20350481 | 0.62 | PAICS (1.00) | PAICS | |
| SCHEMBL15884971 | 0.61 | PIM2 (0.40) | PAICSMETBRD4CREBBPFGFR1 | |
| SCHEMBL19005196 | 0.60 | PIK3CD (0.55) | PAICSCREBBPFGFR1TTK | |
| SCHEMBL24491469 | 0.60 | CHRNB2 (0.41) | PAICS | |
| SCHEMBL24026955 | 0.60 | PIK3CD (0.39) | PAICSTTK | |
| SCHEMBL16721702 | 0.58 | BRD4 (0.47) | PAICSBRD4CREBBPFGFR1 | |
| SCHEMBL22919044 | 0.58 | USP30 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122550-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |