SCHEMBL20352830

SCHEMBL20352830

COc1ccnc(C(=O)N[C@@H](C)C(=O)O[C@@H](C)[C@@H](c2ccccc2)C2CCCC2)c1OCOC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.34
▸ ALDH1A1 P00352 3/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ ALK Q9UM73 2/20 0.33
▸ IGF1R P08069 1/20 0.33
▸ MAPT P10636 3/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ TSHR P16473 1/20 0.33
▸ CTSA P10619 1/20 0.33
▸ KCNA5 P22460 1/20 0.32
▸ AGTR2 P50052 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ AXL P30530 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20352695 1.00 MEN1 (0.34) MEN1ALDH1A1KMT2AMAPK1ALK
SCHEMBL20352740 0.91 ALDH1A1 (0.35) MEN1ALDH1A1KMT2AMAPK1ALK
SCHEMBL20352972 0.91 ALDH1A1 (0.35) MEN1ALDH1A1KMT2AMAPK1ALK
SCHEMBL20352680 0.89 XBP1 (0.32) TDP1
SCHEMBL20352970 0.89 FFAR1 (0.32) TSHRAXL
SCHEMBL20858514 0.88 TDP1 (0.34) MEN1ALDH1A1KMT2AMAPTTDP1
SCHEMBL17905438 0.88 ALDH1A1 (0.33) MEN1ALDH1A1KMT2AMAPK1MAPT
SCHEMBL17905135 0.87 RAB9A (0.33) MEN1ALDH1A1KMT2AMAPK1MAPT
SCHEMBL20352863 0.87 MAPT (0.36) MEN1ALDH1A1KMT2AMAPTTDP1
SCHEMBL17902276 0.87 TDP1 (0.38) MEN1ALDH1A1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3565410-B1 PICOLINAMIDES AS FUNGICIDES CORTEVA AGRISCIENCE LLC (US) 2023-02-15 — — EP disclosed
US-10246417-B2 Picolinamides as fungicides DOW AGROSCIENCES LLC (US) 2019-04-02 — — US disclosed
US-20180186742-A1 PICOLINAMIDES AS FUNGICIDES DOW AGROSCIENCES LLC (US) 2018-07-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10246417-B2 Picolinamides as fungicides CYP1A2, CYP4F12, FKBP2 MEN1 2009/4885ALDH1A1 1130/4885KMT2A 2803/4885
US-20180186742-A1 PICOLINAMIDES AS FUNGICIDES CYP1A2, CYP4F12, FKBP2 MEN1 2009/4885ALDH1A1 1130/4885KMT2A 2803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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