Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20352659 | 1.00 | TSHR (0.34) | TSHRALKIGF1RALDH1A1KMT2A | |
| SCHEMBL29443131 | 1.00 | TSHR (0.34) | TSHRALKIGF1RALDH1A1KMT2A | |
| SCHEMBL20352740 | 0.92 | ALDH1A1 (0.35) | TSHRALKIGF1RALDH1A1KMT2A | |
| SCHEMBL20352972 | 0.92 | ALDH1A1 (0.35) | TSHRALKIGF1RALDH1A1KMT2A | |
| SCHEMBL25021283 | 0.89 | ALDH1A1 (0.33) | ALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL21339315 | 0.89 | ALDH1A1 (0.33) | ALDH1A1KMT2AMAPK1NPSR1 | |
| SCHEMBL20352628 | 0.88 | ALDH1A1 (0.35) | ALKIGF1RALDH1A1KMT2AMEN1 | |
| SCHEMBL20352650 | 0.88 | ALDH1A1 (0.35) | ALKIGF1RALDH1A1KMT2AMEN1 | |
| SCHEMBL29443149 | 0.88 | ALDH1A1 (0.35) | ALKIGF1RALDH1A1KMT2AMEN1 | |
| SCHEMBL20352830 | 0.83 | MEN1 (0.34) | TSHRALKIGF1RALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565410-B1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-02-15 | — | — | EP | disclosed |
| US-10246417-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018129237-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018129238-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | TSHR 2350/4885ALK 1886/4885IGF1R 2485/4885 |
| US-10246417-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | TSHR 2350/4885ALK 1886/4885IGF1R 2485/4885 |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | TSHR 2350/4885ALK 1886/4885IGF1R 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.