Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 8/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20353098 | 0.87 | KCNH2 (0.44) | FTOJAK2HDAC6ALBNT5E | |
| SCHEMBL20353152 | 0.83 | FTO (0.55) | FTOJAK2HDAC6ALBMEN1 | |
| SCHEMBL7877596 | 0.82 | FTO (0.52) | FTOJAK2HDAC6ALBNT5E | |
| SCHEMBL28607477 | 0.81 | FTO (0.53) | FTOJAK2HDAC6ALBNT5E | |
| SCHEMBL26030595 | 0.80 | FTO (0.52) | FTOJAK2HDAC6ALBNT5E | |
| SCHEMBL26030621 | 0.80 | JAK2 (0.51) | FTOJAK2HDAC6ALBNT5E | |
| SCHEMBL25362908 | 0.79 | FTO (0.51) | FTOJAK2HDAC6ALBNT5E | |
| SCHEMBL314241 | 0.79 | ALB (0.51) | FTOJAK2HDAC6ALBNT5E | |
| SCHEMBL19835756 | 0.79 | FTO (0.53) | FTOJAK2HDAC6ALBNT5E | |
| SCHEMBL21549529 | 0.79 | FTO (0.50) | FTOJAK2HDAC6ALBNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125992-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | PROMEGA CORPORATION (US) | 2018-07-05 | — | — | WO | disclosed |