Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25457426 | 0.90 | KCNH2 (0.46) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL21549540 | 0.88 | TP53 (0.46) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL21549531 | 0.88 | TP53 (0.46) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL20353259 | 0.87 | FTO (0.46) | HDAC6HDAC1HDAC10HDAC2HDAC8 | |
| SCHEMBL23509569 | 0.83 | KCNH2 (0.48) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL22600489 | 0.83 | KCNH2 (0.47) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL16745258 | 0.83 | P2RY6 (0.42) | KCNH2FTOALDH1A1HPGDTDP1 | |
| SCHEMBL21549533 | 0.82 | KCNH2 (0.43) | KCNH2HDAC6HDAC1HDAC10HDAC2 | |
| SCHEMBL18270247 | 0.82 | CYP3A4 (0.48) | KCNH2FTOALBALDH1A1HPGD | |
| SCHEMBL29923531 | 0.81 | KCNH2 (0.41) | KCNH2FTONT5EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018125992-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | PROMEGA CORPORATION (US) | 2018-07-05 | — | — | WO | disclosed |