Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15578063 | 0.85 | HDAC1 (0.61) | HDAC1HDAC2CYP1A2ADORA2AADORA1 | |
| SCHEMBL19407338 | 0.83 | NPSR1 (0.64) | HDAC1HDAC2CYP1A2ADORA2AADORA1 | |
| SCHEMBL29858336 | 0.83 | NPSR1 (0.64) | HDAC1HDAC2CYP1A2ADORA2AADORA1 | |
| SCHEMBL933223 | 0.81 | HDAC1 (0.64) | HDAC1HDAC2CYP1A2ADORA2AADORA1 | |
| SCHEMBL20353962 | 0.80 | CYP1A2 (0.61) | HDAC1HDAC2CYP1A2ADORA2AADORA1 | |
| SCHEMBL31536348 | 0.80 | HDAC1 (0.56) | HDAC1HDAC2CYP1A2ADORA2AADORA1 | |
| SCHEMBL7759109 | 0.77 | CYP1A2 (0.63) | HDAC1HDAC2CYP1A2ALDH1A1GAA | |
| SCHEMBL11700881 | 0.77 | HDAC1 (0.53) | HDAC1HDAC2CYP1A2ADORA2AADORA1 | |
| SCHEMBL5547093 | 0.77 | HDAC1 (0.55) | HDAC1HDAC2CYP1A2HDAC8HDAC6 | |
| SCHEMBL24943587 | 0.76 | HDAC1 (0.55) | HDAC1HDAC2CYP1A2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | HDAC1 1020/4885HDAC2 698/4885CYP1A2 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.