Malinamide

Malinamide

SCHEMBL20354

CCCCC/C=C\C/C=C\CCCCCCCC(=O)NC(C)c1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.62
FAAH O00519 2/20 0.62
CNR2 P34972 2/20 0.62
CNR1 P21554 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.61
SOAT2 O75908 1/20 0.61
SOAT1 P35610 1/20 0.61
SLC6A5 Q9Y345 1/20 0.61
ALDH1A1 P00352 2/20 0.60
ASAH1 Q13510 1/20 0.60
ACER2 Q5QJU3 1/20 0.60
KCNK3 O14649 1/20 0.57
THRB P10828 1/20 0.57
BLM P54132 1/20 0.57
TDP1 Q9NUW8 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Melinamide SCHEMBL1650618 1.00 EPHX2 (0.62) EPHX2FAAHCNR2CNR1SMN1; SMN2
Malinamide SCHEMBL5015625 0.98 EPHX2 (0.60) EPHX2FAAHCNR2CNR1SMN1; SMN2
SCHEMBL11857434 0.97 SOAT2 (0.64) EPHX2FAAHCNR2CNR1SMN1; SMN2
SCHEMBL11857445 0.97 SOAT2 (0.64) EPHX2FAAHCNR2CNR1SMN1; SMN2
SCHEMBL11859859 0.93 EPHX2 (0.62) EPHX2FAAHCNR2CNR1SMN1; SMN2
Malinamide SCHEMBL15955718 0.91 EPHX2 (0.54) EPHX2FAAHCNR2CNR1SMN1; SMN2
SCHEMBL4183115 0.89 ALDH1A1 (0.72) FAAHALDH1A1ASAH1ACER2
SCHEMBL4139311 0.89 ALDH1A1 (0.72) FAAHALDH1A1ASAH1ACER2
SCHEMBL4139305 0.89 ALDH1A1 (0.72) FAAHALDH1A1ASAH1ACER2
SCHEMBL9472620 0.89 ALDH1A1 (0.72) FAAHALDH1A1ASAH1ACER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5486 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076601-A1 HAND SCREW SILVA ADAIRTO (BR) 2025-04-17 WO claimed
WO-2024210735-A1 TRANSPARENT ADHESIVE POLYMER FILM WITH INTEGRATED SECURITY MARKINGS DIAZ LOPEZ, EDUARDO (MX) 2024-10-10 WO claimed
US-11911469-B2 Combination of ACAT1 inhibitor and checkpoint antibody for treating cancer Center for Excellence in Molecular Cell Science, Chinese Academy of Scienes (CN) 2024-02-27 US claimed
WO-2023233053-A1 TRAINING SYSTEM FOR ATHLETES OF MARTIAL ARTS AND CONTACT SPORTS TOSCANO MARTIN DIDAC (ES) 2023-12-07 WO claimed
CN-116829142-A Methods for treating and ameliorating cancer 加利福尼亚大学董事会 2023-09-29 CN claimed
WO-2023170321-A1 TRAMPOLINE FOR VIRTUAL REALITY OR OTHER SIMILAR SIMULATED ENVIRONMENTS HOLGERSSON ZEGARRA PEER (ES) 2023-09-14 WO claimed
CN-116077483-A Pharmaceutical use of chinaberry amide and analogues thereof 上海中医药大学 2023-05-09 CN claimed
CN-115778935-A Application of melinamide in preparation of medicine for preventing and/or treating porcine reproductive and respiratory syndrome 中山大学 2023-03-14 CN claimed
US-11571400-B2 ACAT1 inhibitors for treating cancer CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) 2023-02-07 US claimed
WO-2022098795-A1 ANTIPATHOGENIC PERSONAL PROTECTIVE EQUIPMENT (PPE) ADVANCEDMEMS LLC (US) 2022-05-12 WO claimed
CN-1174701-A Skin protective composition containing methylbenzyl amine linoleic and visual yellow acid like UNILEVER NV (NL) 1998-03-04 CN claimed
US-5693330-A SKIN CONDITIONERS; SYNERGISTIC ENHANCEMENT OF KERATINOCYTE PROLIFERATION ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) 1997-12-02 US claimed
EP-0803247-A2 Skin care compositions containing a retinoid UNILEVER PLC (GB) 1997-10-29 EP claimed
WO-1997027847-A1 METHOD OF TREATING DIABETES AND RELATED DISEASE STATES MERCK & CO., INC. (US) 1997-08-07 WO claimed
WO-1997027857-A1 ANTIDIABETIC AGENTS MERCK & CO., INC. (US) 1997-08-07 WO claimed
WO-1997028137-A1 HETEROCYCLIC DERIVATIVES AS ANTIDIABETIC AND ANTIOBESITY AGENTS MERCK & CO., INC. (US) 1997-08-07 WO claimed
WO-1997028115-A1 ANTIDIABETIC AGENTS MERCK & CO., INC. (US) 1997-08-07 WO claimed
EP-0554632-B1 Releasable split bearing METALLISED CARBON CORP (US) 1996-04-24 EP claimed
WO-1991007727-A1 SYSTEM OF COMBINED DIGITAL PHOTOGRAPHIES GARCIA BARRIO MIGUEL ANGEL (ES) 1991-05-30 WO claimed
US-3962436-A Pharmaceutical compositions having controlled rate of gastro-intestinal absorption SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-06-08 US claimed