Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.64 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.62 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.62 |
| ▸ | FAAH | O00519 | 6/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11857434 | 1.00 | SOAT2 (0.64) | SOAT2SOAT1ALDH1A1ASAH1ACER2 | |
| Malinamide SCHEMBL20354 | 0.97 | EPHX2 (0.62) | SOAT2SOAT1ALDH1A1ASAH1ACER2 | |
| Melinamide SCHEMBL1650618 | 0.97 | EPHX2 (0.62) | SOAT2SOAT1ALDH1A1ASAH1ACER2 | |
| Malinamide SCHEMBL5015625 | 0.95 | EPHX2 (0.60) | SOAT2SOAT1ALDH1A1ASAH1ACER2 | |
| SCHEMBL4183115 | 0.92 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2FAAHMAPT | |
| SCHEMBL9472620 | 0.92 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2FAAHMAPT | |
| SCHEMBL5599045 | 0.92 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2FAAHMAPT | |
| SCHEMBL4139305 | 0.92 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2FAAHMAPT | |
| SCHEMBL4139311 | 0.92 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2FAAHMAPT | |
| SCHEMBL16714723 | 0.92 | ALDH1A1 (0.72) | ALDH1A1ASAH1ACER2FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3995059-A | CHOLESTEROL LOWERING AGENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-11-30 | — | — | US | disclosed |