Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013908 | 0.83 | CHEK2 (0.48) | OPRK1 | |
| SCHEMBL29796027 | 0.82 | KDM1A (0.58) | GPR119PDE4B | |
| SCHEMBL520668 | 0.82 | KDM1A (0.58) | GPR119PDE4B | |
| SCHEMBL3292130 | 0.81 | OPRK1 (0.49) | OPRK1 | |
| SCHEMBL4373488 | 0.80 | GPR119 (0.54) | GPR119CHRM2 | |
| Hydrochloric Acid SCHEMBL4373751 | 0.79 | GPR119 (0.53) | GPR119CHRM2 | |
| SCHEMBL30996477 | 0.79 | P2RY12 (0.46) | GPR119OPRK1 | |
| SCHEMBL30996476 | 0.79 | P2RY12 (0.46) | GPR119OPRK1 | |
| SCHEMBL2333100 | 0.78 | GPR119 (0.78) | GPR119CHRM2PDE4B | |
| SCHEMBL2334301 | 0.78 | GPR119 (0.68) | GPR119CHRM2PDE4BOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018124001-A1 | BMP-SIGNAL-INHIBITING COMPOUND | 国立研究開発法人理化学研究所 | 2018-07-05 | — | — | WO | disclosed |