Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292130 | 0.87 | OPRK1 (0.49) | OPRK1EPHX2KMT2AMEN1 | |
| SCHEMBL2093978 | 0.86 | EPHX2 (0.60) | PIK3CDIKBKBHRH3EPHX2CHUK | |
| SCHEMBL13097134 | 0.86 | CHRM3 (0.52) | OPRK1IKBKBHRH3EPHX2CHUK | |
| SCHEMBL12377876 | 0.86 | EPHX2 (0.60) | IKBKBHRH3EPHX2KMT2A | |
| SCHEMBL2091338 | 0.83 | EPHX2 (0.57) | IKBKBEPHX2CHUKCYP4F2CYP4A11 | |
| SCHEMBL29796027 | 0.83 | KDM1A (0.58) | CHEK2HRH3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9013948 | 0.83 | OPRK1 (0.51) | PIK3CDOPRK1IKBKBHRH3KMT2A | |
| SCHEMBL20354515 | 0.83 | GPR119 (0.59) | OPRK1 | |
| SCHEMBL520668 | 0.83 | KDM1A (0.58) | CHEK2HRH3KMT2AMEN1 | |
| SCHEMBL9013886 | 0.82 | CASP6 (0.53) | CHEK2IKBKBHRH3CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580883-A | INHIBITING DEGENERATION AND NECROCYTOSIS OF CEREBRAL NERVE CELLS CAUSED BY OXIDATIVE STRESS INDUCING GLUTAMIC ACID IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0449195-B1 | Aminobenzene compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0449195-A2 | Aminobenzene compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |