Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355133 | 0.94 | KMT2A (0.44) | LMNAPKMMEN1KMT2ATSHR | |
| SCHEMBL20355346 | 0.92 | KMT2A (0.48) | LMNAPKMNR4A2MEN1KMT2A | |
| SCHEMBL29560193 | 0.92 | CCR2 (0.46) | LMNAMEN1KMT2AKIT | |
| SCHEMBL20354838 | 0.92 | KMT2A (0.46) | LMNAPKMMEN1KMT2ATSHR | |
| SCHEMBL20340322 | 0.92 | CCR2 (0.49) | MEN1KMT2ATSHRKIT | |
| SCHEMBL20354691 | 0.92 | CCR2 (0.46) | LMNAMEN1KMT2AKIT | |
| SCHEMBL26784610 | 0.90 | MAPT (0.47) | LMNAMEN1KMT2AHTR2AGAA | |
| SCHEMBL20355075 | 0.90 | LMNA (0.39) | LMNAPKMMEN1KMT2ATSHR | |
| SCHEMBL20354831 | 0.86 | ACLY (0.45) | LMNAPKMMEN1KMT2ANR3C1 | |
| SCHEMBL29559687 | 0.86 | ACLY (0.45) | LMNAPKMMEN1KMT2ANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |