Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355040 | 0.76 | GPR17 (0.38) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20354734 | 0.76 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20354836 | 0.76 | IDO1 (0.38) | ALDH1A1KDM4EHSD17B10IDO1NR4A2 | |
| SCHEMBL29955110 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10IDO1 | |
| SCHEMBL20354828 | 0.74 | TRPV4 (0.37) | ALDH1A1KDM4EHSD17B10IDO1NR4A2 | |
| SCHEMBL20339034 | 0.73 | STAT3 (0.38) | ALDH1A1KDM4EHSD17B10IDO1NR4A2 | |
| SCHEMBL20355295 | 0.72 | NOTUM (0.35) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20354849 | 0.69 | AR (0.47) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL27296153 | 0.65 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10HTR2CTSHR | |
| SCHEMBL27960290 | 0.64 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |