Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355040 | 0.79 | GPR17 (0.38) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20354734 | 0.76 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21569548 | 0.74 | NOTUM (0.34) | NOTUMCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20354849 | 0.72 | AR (0.47) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20355225 | 0.72 | ALDH1A1 (0.37) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21569511 | 0.65 | HSD17B10 (0.53) | — | |
| SCHEMBL20355273 | 0.62 | TNF (0.48) | NOTUMCSNK2A1 | |
| SCHEMBL17027274 | 0.62 | IDO1 (0.48) | — | |
| SCHEMBL20354815 | 0.61 | GPR84 (0.53) | — | |
| SCHEMBL4921456 | 0.59 | NOTUM (0.45) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |