Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16139278 | 0.84 | HSD17B10 (0.53) | HSD17B10CYP1A2MEN1KMT2ACYP3A4 | |
| SCHEMBL6422898 | 0.80 | HSD17B10 (0.62) | HSD17B10CYP1A2MEN1KMT2ACYP3A4 | |
| SCHEMBL20881126 | 0.80 | SIGMAR1 (0.45) | MEN1KMT2ACYP3A4CYP2C19CYP2D6 | |
| SCHEMBL14465838 | 0.78 | MAPT (0.50) | HSD17B10MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL27390003 | 0.78 | HSD17B10 (0.55) | HSD17B10CYP1A2MEN1KMT2ACYP3A4 | |
| SCHEMBL2502058 | 0.78 | RAB9A (0.69) | HSD17B10CYP1A2MEN1KMT2ACYP3A4 | |
| SCHEMBL1740852 | 0.77 | CYP1A2 (0.67) | HSD17B10CYP1A2MEN1KMT2ACYP3A4 | |
| SCHEMBL14432349 | 0.77 | HSD17B10 (0.58) | HSD17B10CYP1A2MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL23721867 | 0.76 | RAB9A (0.67) | HSD17B10CYP1A2MEN1KMT2ACYP3A4 | |
| SCHEMBL4648147 | 0.76 | POLB (0.52) | CYP1A2MEN1KMT2ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122775-A1 | HETEROARYL COMPOUNDS AND THEIR USE | MINORYX THERAPEUTICS S.L. (ES) | 2018-07-05 | — | — | WO | disclosed |