Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21469972 | 0.95 | NPC1 (0.46) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL20358292 | 0.83 | NPC1 (0.57) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL20357895 | 0.83 | NPC1 (0.57) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL20358080 | 0.83 | NPC1 (0.57) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL28925264 | 0.83 | NPC1 (0.57) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL28652692 | 0.83 | NPC1 (0.57) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL16564290 | 0.82 | NPC1 (0.59) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL16563220 | 0.77 | NPC1 (0.51) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL20365744 | 0.77 | NPC1 (0.61) | NPC1RAB9ANTSR1RCE1USP2 | |
| SCHEMBL20357007 | 0.72 | NPC1 (0.51) | NPC1RAB9ANTSR1RCE1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345981-B1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INT (FR) | 2020-09-09 | — | — | EP | disclosed |
| US-10730855-B2 | Electrochromic compounds and optical articles containing them | ESSILOR INTERNATIONAL (FR) | 2020-08-04 | — | — | US | disclosed |
| US-20190315718-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (FR) | 2019-10-17 | — | — | US | disclosed |
| EP-3345981-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | Essilor International (FR) | 2018-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730855-B2 | Electrochromic compounds and optical articles containing them | EYA2, EYA3, ALDH1A2 | NPC1 4544/4885RAB9A 1110/4885NTSR1 4009/4885 |
| US-20190315718-A1 | ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM | EYA2, EYA3, ALDH1A2 | NPC1 4544/4885RAB9A 1110/4885NTSR1 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.