Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357208 | 1.00 | MDM4 (0.50) | MDM4TP53MDM2HDAC1HDAC2 | |
| SCHEMBL29992297 | 0.88 | KMT2A (0.51) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL17826038 | 0.88 | KMT2A (0.51) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL10022278 | 0.87 | MDM2 (0.52) | MDM4TP53MDM2CASP3 | |
| SCHEMBL29991547 | 0.86 | CASP3 (0.53) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL16463752 | 0.86 | MDM2 (0.58) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL20530570 | 0.86 | MDM2 (0.58) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL30471464 | 0.85 | MDM4 (0.52) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL27872890 | 0.84 | MDM4 (0.51) | MDM4TP53MDM2KMT2ACASP3 | |
| SCHEMBL13561436 | 0.83 | HDAC1 (0.60) | MDM4TP53MDM2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345917-B1 | ANTIPROTOZOAL COMPOUNDS | BACOBA AG (CH) | 2021-11-17 | — | — | EP | disclosed |
| EP-3345917-A1 | ANTIPROTOZOAL COMPOUNDS | Bacoba AG (CH) | 2018-07-11 | — | — | EP | disclosed |