Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29991547 | 0.91 | CASP3 (0.53) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL8303670 | 0.87 | MDM4 (0.50) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL30384784 | 0.87 | MDM4 (0.50) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL29008318 | 0.87 | MDM4 (0.50) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL15356432 | 0.86 | MDM4 (0.49) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL30471464 | 0.86 | MDM4 (0.52) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL119442 | 0.85 | MDM4 (0.58) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL119451 | 0.85 | MDM4 (0.58) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL29401991 | 0.85 | MDM4 (0.58) | MDM4TP53CASP3KMT2AMDM2 | |
| SCHEMBL29370319 | 0.85 | MDM4 (0.58) | MDM4TP53CASP3KMT2AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702343-A | Method for synthesizing tesamorelin through solid phases | GL BIOCHEM SHANGHAI CO LTD | 2012-10-03 | — | — | CN | claimed |
| CN-102702343-A | Method for synthesizing tesamorelin through solid phases | GL BIOCHEM SHANGHAI CO LTD | 2012-10-03 | — | — | CN | disclosed |