Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.45 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2035982 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3ACACBPDE2A | |
| Sulfuric Acid SCHEMBL4623897 | 1.00 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3ACACBPDE2A | |
| SCHEMBL2031199 | 0.89 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3ACACBPDE2A | |
| SCHEMBL2034831 | 0.89 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3ACACBPDE2A | |
| SCHEMBL2034762 | 0.89 | SLC6A4 (0.53) | SLC6A2SLC6A4SLC6A3ACACBPDE2A | |
| Hydrochloric Acid SCHEMBL14120624 | 0.87 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ACACBPDE2A | |
| Hydrochloric Acid SCHEMBL14157331 | 0.87 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ACACBPDE2A | |
| Ammonia Solution, Strong SCHEMBL27705195 | 0.77 | ACACB (0.43) | SLC6A2SLC6A4SLC6A3ACACBCA1 | |
| SCHEMBL8413205 | 0.76 | PPARA (0.59) | PPARA | |
| SCHEMBL14465633 | 0.75 | KDM4E (0.52) | SLC6A2SLC6A4SLC6A3ACACBELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968328-B2 | Method for producing optically active aminoalkylphenols | BASF SE (DE) | 2011-06-28 | — | — | US | disclosed |
| US-20100209980-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINOALKYLPHENOLS | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-19 | — | — | US | disclosed |