Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515800 | 0.80 | PTGS1 (0.52) | PTGS1PTGS2LMNATSHRPMP22 | |
| SCHEMBL20362145 | 0.79 | GSK3A (0.47) | PTGS1PTGS2LMNAPMP22SMN1; SMN2 | |
| Bromoacetic Acid SCHEMBL9701974 | 0.78 | PTGS1 (0.86) | PTGS1PTGS2LMNATSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL28991159 | 0.78 | PTGS1 (0.50) | PTGS1PTGS2LMNATSHRPMP22 | |
| SCHEMBL24939859 | 0.77 | PTGS1 (1.00) | PTGS1PTGS2LMNATSHRNFKB1 | |
| SCHEMBL1574552 | 0.77 | PTGS1 (1.00) | PTGS1PTGS2LMNATSHRNFKB1 | |
| SCHEMBL8779419 | 0.77 | PTGS1 (1.00) | PTGS1PTGS2LMNATSHRNFKB1 | |
| SCHEMBL43882 | 0.77 | PTGS1 (1.00) | PTGS1PTGS2LMNATSHRNFKB1 | |
| SCHEMBL8779453 | 0.77 | PTGS1 (1.00) | PTGS1PTGS2LMNATSHRNFKB1 | |
| SCHEMBL43969 | 0.77 | PTGS1 (1.00) | PTGS1PTGS2LMNATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018129203-A2 | METHOD FOR TEMPORAL AND TISSUE-SPECIFIC DRUG DELIVERY AND INDUCED NUCLEIC ACID RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-07-12 | — | — | WO | disclosed |