SCHEMBL515800

SCHEMBL515800

O=C(O)CN1C(=O)C=CC1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 5/20 0.52
PTGS2 P35354 5/20 0.52
GSK3A P49840 2/20 0.52
GSK3B P49841 2/20 0.52
CA12 O43570 1/20 0.50
CA9 Q16790 1/20 0.50
MGLL Q99685 5/20 0.46
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
FAAH O00519 3/20 0.46
LMNA P02545 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
BLM P54132 2/20 0.46
GMNN O75496 1/20 0.46
THPO P40225 1/20 0.46
PMP22 Q01453 1/20 0.46
TSHR P16473 1/20 0.45
HPGD P15428 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HSP90AA1 P07900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28991159 0.97 PTGS1 (0.50) PTGS1PTGS2GSK3AGSK3BCA12
Ethylene Glycol SCHEMBL28669577 0.93 PTGS1 (0.47) PTGS1PTGS2GSK3AGSK3BCA12
Alcohol SCHEMBL29133233 0.91 GSK3A (0.55) PTGS1PTGS2GSK3AGSK3BCA12
1,4-Butanediol SCHEMBL5570451 0.89 PTGS1 (0.48) PTGS1PTGS2GSK3AGSK3BCA12
SCHEMBL1055378 0.84 TSHR (0.43) PTGS1PTGS2GSK3AGSK3BCA12
Succinimide SCHEMBL27157818 0.84 TSHR (0.43) PTGS1PTGS2GSK3AGSK3BCA12
SCHEMBL28667104 0.82 MGLL (0.50) PTGS1PTGS2GSK3AGSK3BCA12
SCHEMBL1103791 0.80 GSK3A (0.48) PTGS1PTGS2GSK3AGSK3BMGLL
SCHEMBL2382060 0.80 PTGS1 (0.53) PTGS1PTGS2GSK3AGSK3BMGLL
SCHEMBL20362146 0.80 PTGS1 (0.62) PTGS1PTGS2GSK3AGSK3BCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 862 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025243208-A2 PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF POLYETHYLENE GLYCOL AND ITS DERIVATIVES, OBTAINED PRODUCT AND USES THEREOF HOVIONE - FARMACIÊNCIA, SA (PT) 2025-11-27 WO claimed
CN-120005123-A Acrylic ester block copolymer resin, photoresist, and preparation method and application thereof 中国石油化工股份有限公司 2025-05-16 CN claimed
CN-119823209-A Synthesis method of cyclic peptide containing maleimide acid 江苏金斯瑞生物科技有限公司 2025-04-15 CN claimed
CN-119716071-A Nanopore detection probe generated by connecting target molecules to be detected and load molecules, and preparation method and application thereof 中国科学院化学研究所 2025-03-28 CN claimed
EP-4251210-B1 MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S R L (IT) 2025-03-19 EP claimed
EP-4251211-B1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXIC DRUGS ANBITION S R L (IT) 2025-02-26 EP claimed
CN-116284766-B Maleimide functionalized polyethyleneimine and preparation and application thereof 华中科技大学 2024-12-31 CN claimed
CN-118772528-A Polypropylene composition and polypropylene prepared from same 国家能源投资集团有限责任公司 2024-10-15 CN claimed
CN-117457312-A Magnetic molecular probe for specifically capturing metabolites from complex sample, and preparation method and application thereof 中国医学科学院基础医学研究所 2024-01-26 CN claimed
US-20240000967-A1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S.R.L. (IT) 2024-01-04 US claimed
EP-2315771-A2 GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF Sloan Kettering Institute For Cancer Research (US) 2011-05-04 EP claimed
WO-2010006343-A2 GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2010-01-14 WO claimed
EP-0996455-B1 ALPHA-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF SLOAN KETTERING INST CANCER (US) 2009-12-16 EP claimed
CN-100570458-C Method for manufacturing electrophoretic display device CANON KK (JP) 2009-12-16 CN claimed
US-20090099074-A1 MODULATING FOOD INTAKE CONJUCHEM BIOTECHNOLOGIES INC. (CA) 2009-04-16 US claimed
WO-2008049643-A2 GD2 PEPTIDE MIMOTOPES FOR ANTICANCER VACCINATION CHARITE - UNIVERSITÄTSMEDIZIN BERLIN (DE) 2008-05-02 WO claimed
EP-1916257-A1 GD2 peptide mimotopes for anticancer vaccination Charite-Universitätsmedizin Berlin (DE) 2008-04-30 EP claimed
CN-1705907-A Method for manufacturing electrophoretic display device CANON KK (JP) 2005-12-07 CN claimed
EP-0608445-A1 2,5-Dioxo-3-pyrroline-1-acetanilide fungicidal agents and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1994-08-03 EP claimed
US-5310937-A 2,5-dioxo-3-pyrroline-1-acetanilide fungicidal agents and method for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1994-05-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099074-A1 MODULATING FOOD INTAKE GIPR, VIP, PTMS PTGS1 2881/4885PTGS2 2893/4885GSK3A 4004/4885
US-20240000967-A1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ALB, CD63, ENPEP PTGS1 4141/4885PTGS2 4133/4885GSK3A 3719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.