Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | WRN | Q14191 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 6/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499154 | 0.80 | PTGS1 (0.68) | GSK3AGSK3BPTGS1PTGS2ALDH1A1 | |
| SCHEMBL20362146 | 0.79 | PTGS1 (0.62) | GSK3AGSK3BPTGS1PTGS2ALDH1A1 | |
| SCHEMBL28038312 | 0.78 | PTGS1 (0.66) | GSK3AGSK3BPTGS1PTGS2ALDH1A1 | |
| SCHEMBL6887378 | 0.76 | ALDH1A1 (0.43) | ALDH1A1FAAHLMNAMAPTMAPK1 | |
| SCHEMBL19863302 | 0.76 | ALDH1A1 (0.43) | ALDH1A1FAAHLMNAMAPTMAPK1 | |
| SCHEMBL2495523 | 0.75 | MGLL (0.58) | GSK3AGSK3BPTGS1PTGS2ALDH1A1 | |
| SCHEMBL16579831 | 0.74 | PTGS1 (0.60) | GSK3AGSK3BPTGS1PTGS2ALDH1A1 | |
| SCHEMBL14938147 | 0.74 | ALDH1A1 (0.46) | ALDH1A1FAAHLMNAMAPTMAPK1 | |
| SCHEMBL8197865 | 0.73 | PTGS1 (0.69) | GSK3AGSK3BPTGS1PTGS2ALDH1A1 | |
| SCHEMBL22372519 | 0.73 | PTGS1 (0.73) | GSK3AGSK3BPTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018129203-A2 | METHOD FOR TEMPORAL AND TISSUE-SPECIFIC DRUG DELIVERY AND INDUCED NUCLEIC ACID RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-07-12 | — | — | WO | disclosed |