Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.56 |
| ▸ | ADH1C | P00326 | 1/20 | 0.56 |
| ▸ | ADH1A | P07327 | 1/20 | 0.56 |
| ▸ | ADH4 | P08319 | 1/20 | 0.56 |
| ▸ | ADH7 | P40394 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318789 | 1.00 | ADH1B (0.56) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL8628188 | 0.92 | ADH1B (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL8628191 | 0.92 | ADH1B (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL17706682 | 0.84 | CHRM1 (0.44) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL14819043 | 0.84 | CHRM1 (0.44) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL17951698 | 0.83 | ADH1B (0.53) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL13350892 | 0.82 | ADH1B (0.53) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL13351138 | 0.82 | ADH1B (0.53) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL18583123 | 0.81 | LMNA (0.44) | GPR84NOD1FFAR1 | |
| SCHEMBL17024089 | 0.80 | GPR84 (0.57) | MAPTGPR84NOD1FFAR1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |