Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23685282 | 0.87 | MEN1 (0.43) | KLK5MEN1KMT2AGAATDP1 | |
| SCHEMBL20366319 | 0.85 | MEN1 (0.47) | KLK5MEN1KMT2AGAATDP1 | |
| SCHEMBL10164404 | 0.80 | MEN1 (0.47) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL20366165 | 0.80 | MEN1 (0.42) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL20556183 | 0.79 | MEN1 (0.51) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL15159978 | 0.79 | MEN1 (0.51) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL10129167 | 0.78 | MEN1 (0.43) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL11919227 | 0.77 | MEN1 (0.50) | KLK5MEN1KMT2AGAATDP1 | |
| SCHEMBL21498186 | 0.77 | KMT2A (0.42) | KLK5MEN1KMT2AGAATDP1 | |
| SCHEMBL5761580 | 0.76 | MEN1 (0.59) | MEN1KMT2AGAATDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |