Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20366152 | 0.87 | KLK5 (0.45) | MEN1GAAKMT2ATDP1CYP2D6 | |
| SCHEMBL20366014 | 0.83 | MEN1 (0.44) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL25458901 | 0.80 | NMT2 (0.45) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL18736992 | 0.79 | MEN1 (0.51) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL25458905 | 0.77 | NOD1 (0.37) | — | |
| SCHEMBL2368382 | 0.76 | MEN1 (0.59) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL5761580 | 0.76 | MEN1 (0.59) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL12598786 | 0.76 | MEN1 (0.59) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL26789986 | 0.76 | MEN1 (0.60) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL19033286 | 0.75 | MEN1 (0.55) | MEN1GAAKMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021150792-A1 | NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS | MICURX PHARMACEUTICALS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |