SCHEMBL20366165

SCHEMBL20366165

COC(=O)[C@H](CCNC(=O)OC(C)(C)C)NC(=O)[C@@H](N)[C@@H](C)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 1/20 0.42
TDP1 Q9NUW8 5/20 0.39
ATM Q13315 2/20 0.39
MAPT P10636 2/20 0.38
NPSR1 Q6W5P4 4/20 0.38
POLB P06746 3/20 0.38
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
CTSS P25774 5/20 0.36
CTSK P43235 5/20 0.36
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CAPN1 P07384 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31137882 0.89 MEN1 (0.49) MEN1KMT2AGAATDP1ATM
SCHEMBL20366033 0.85 MEN1 (0.38) MEN1KMT2AGAATDP1ATM
SCHEMBL20366135 0.85 MEN1 (0.38) MEN1KMT2AGAATDP1ATM
SCHEMBL25622664 0.85 MEN1 (0.38) MEN1KMT2AGAATDP1ATM
SCHEMBL25622622 0.85 MEN1 (0.38) MEN1KMT2AGAATDP1ATM
SCHEMBL24593926 0.84 MEN1 (0.39) MEN1KMT2AGAATDP1ATM
SCHEMBL19986282 0.81 MEN1 (0.52) MEN1KMT2AGAATDP1ATM
SCHEMBL21982015 0.81 MEN1 (0.52) MEN1KMT2AGAATDP1ATM
SCHEMBL21982014 0.81 MEN1 (0.52) MEN1KMT2AGAATDP1ATM
SCHEMBL31206803 0.80 TDP1 (0.48) MEN1KMT2AGAATDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-22 US disclosed
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-22 US disclosed
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-22 US disclosed
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-01 US disclosed
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-01 US disclosed
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-06-01 US disclosed
WO-2018128826-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS CIDARA THERAPEUTICS, INC. (US) 2018-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190950-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS FCGR3B, FCGR1A, FCGR2A MEN1 3001/4885KMT2A 4310/4885GAA 2534/4885
US-20230165970-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS FCGR3B, FCGR1A, FCGR2A MEN1 3001/4885KMT2A 4310/4885GAA 2534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.